Protect the killer: CTLs need defenses against the tumor

被引：20

作者：

Freeman, GJ

Sharpe, AH

Kuchroo, VK

机构：

[1] Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Adult Oncol, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA

[3] Harvard Univ, Sch Med, Brigham & Womens Hosp, Ctr Neurol Dis, Boston, MA 02115 USA

来源：

NATURE MEDICINE | 2002年 / 8卷 / 08期

关键词：

D O I：

10.1038/nm0802-787

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Evasion of the immune system is an all too common feature of cancer. A new study suggests one evasion mechanism: induction of T-cell apoptosis through B7-H1, a molecule expressed on the surface of many tumor cells ( pages 793 - 800).

引用

页码：787 / 789

页数：4

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