Analgesic and anti-inflammatory effects of the aqueous extract of leaves of Persea americana Mill (Lauraceae)

被引：114

作者：

Adeyemi, OO ^{[1
]}

Okpo, SO ^{[1
]}

Ogunti, OO ^{[1
]}

机构：

[1] Univ Lagos, Coll Med, Dept Pharmacol, Lagos, Nigeria

来源：

FITOTERAPIA | 2002年 / 73卷 / 05期

关键词：

Persea americana; anti-inflammatory; analgesic effects;

D O I：

10.1016/S0367-326X(02)00118-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

The aqueous extract of Persea americana leaves produced a dose-dependent inhibition of both phases of formalin pain test in mice, a reduction in mouse writhing induced by acetic acid and an elevation of pain threshold in the hot plate test in mice. The extract also produced a dose-dependent inhibition of carrageenan-induced rat paw oedema. The results obtained indicate that the extract possesses analgesic and anti-inflammatory effects. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：375 / 380

页数：6

共 13 条

[1]

Bamgbose SO, 1981, PLANTA MED, V42, P392

[2]

STUDIES OF MEDIATORS OF ACUTE INFLAMMATORY RESPONSE INDUCED IN RATS IN DIFFERENT SITES BY CARRAGEENAN AND TURPENTINE [J].