During development, vertebrate embryos undergo dramatic changes in shape. The lengthening and narrowing of a field of cells, termed convergent extension, contributes to a variety of morphogenetic processes. Focusing on frogs and fish, we review the different cellular mechanisms and the well-conserved signaling pathways that underlie this process.
机构:
Pohang Univ Sci & Technol, Div Mol & Life Sci, Pohang 790784, Kyungbuk, South KoreaPohang Univ Sci & Technol, Div Mol & Life Sci, Pohang 790784, Kyungbuk, South Korea
机构:
Pohang Univ Sci & Technol, Div Mol & Life Sci, Pohang 790784, Kyungbuk, South KoreaPohang Univ Sci & Technol, Div Mol & Life Sci, Pohang 790784, Kyungbuk, South Korea