Convergent extension: The molecular control of polarized cell movement during embryonic development

被引:465
作者
Wallingford, JB
Fraser, SE
Harland, RM
机构
[1] Univ Calif Berkeley, Dept Cell & Mol Biol, Berkeley, CA 94720 USA
[2] CALTECH, Beckman Inst, Pasadena, CA 91125 USA
[3] CALTECH, Div Biol, Pasadena, CA 91125 USA
关键词
D O I
10.1016/S1534-5807(02)00197-1
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
During development, vertebrate embryos undergo dramatic changes in shape. The lengthening and narrowing of a field of cells, termed convergent extension, contributes to a variety of morphogenetic processes. Focusing on frogs and fish, we review the different cellular mechanisms and the well-conserved signaling pathways that underlie this process.
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页码:695 / 706
页数:12
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