Mass spectrometric studies on the inhibition of TEM-2 beta-lactamase by clavulanic acid derivatives

被引：8

作者：

Brown, RPA

Aplin, RT

Schofield, CJ

Frydrych, CH

机构：

[1] DYSON PERRINS LAB,OXFORD OX1 3QY,ENGLAND

[2] OXFORD CTR MOL SCI,OXFORD OX1 3QY,ENGLAND

[3] SMITHKLINE BEECHAM PHARMACEUT,BETCHWORTH RH3 7AJ,SURREY,ENGLAND

来源：

JOURNAL OF ANTIBIOTICS | 1997年 / 50卷 / 02期

关键词：

D O I：

10.7164/antibiotics.50.184

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：184 / 185

页数：2

共 8 条

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Aplin, RT ;

Schofield, CJ .

BIOCHEMISTRY, 1996, 35 (38) :12421-12432

[2]

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[3] INACTIVATION OF RTEM BETA-LACTAMASE FROM ESCHERICHIA-COLI BY CLAVULANIC ACID AND 9-DEOXYCLAVULANIC ACID [J].

CHARNAS, RL ;

KNOWLES, JR .

BIOCHEMISTRY, 1981, 20 (11) :3214-3219

[4] INHIBITION OF BETA-LACTAMASE BY CLAVULANATE - TRAPPED INTERMEDIATES IN CRYOCRYSTALLOGRAPHIC STUDIES [J].

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HERZBERG, O .

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[5] INACTIVATION OF CLASS-A BETA-LACTAMASES BY CLAVULANIC ACID - THE ROLE OF ARGININE-244 IN A PROPOSED NONCONCERTED SEQUENCE OF EVENTS [J].

IMTIAZ, U ;

BILLINGS, E ;

KNOX, JR ;

MANAVATHU, EK ;

LERNER, SA ;

MOBASHERY, S .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (11) :4435-4442

[6] PENICILLIN RESISTANCE - THE CHEMISTRY OF BETA-LACTAMASE INHIBITION [J].

KNOWLES, JR .

ACCOUNTS OF CHEMICAL RESEARCH, 1985, 18 (04) :97-104

[7] CLAVULANIC ACID - BETA-LACTAMASE-INHIBITING BETA-LACTAM FROM STREPTOMYCES-CLAVULIGERUS [J].

READING, C ;

COLE, M .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1977, 11 (05) :852-857

[8]

READING C, 1979, BIOCHEM J, V17, P67

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