The published DNA sequence of human cytomegalovirus strain AD169 lacks 929 base pairs affecting genes UL42 and UL43

被引：34

作者：

Dargan, DJ

Jamieson, FE

Maclean, J

Dolan, A

Addison, C

McGeoch, DJ

机构：

来源：

JOURNAL OF VIROLOGY | 1997年 / 71卷 / 12期

关键词：

D O I：

10.1128/JVI.71.12.9833-9836.1997

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Compared with the published DNA sequence (M. S. Chee, et al. Curr. Top. Microbiol. Immunol. 154:125-170, 1990), most isolates of human cytomegalovirus strain AD169 contain an additional 929 dp after nucleotide 54612. This results in a changed reading frame for the 5'-terminal 50 codons of gene UL42 and expansion of gene UL43 (a US22 family member) from 187 (3'-truncated) to 423 (full-length) codons. The UL42 and UL43 gene products are nonessential for growth in culture.

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页码：9833 / 9836

页数：4

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