学术探索
学术期刊
新闻热点
数据分析
智能评审

Misoprostol and active management of the third stage of labor

被引：18
作者：
Prata, N.
Hamza, S.
Gypson, R.
Nada, K.
Vahidnia, F.
Potts, M.
机构：
[1] Univ Calif Berkeley, Sch Publ Hlth, Bixby Program Populat Family Planning & Maternal, Berkeley, CA 94720 USA
[2] John Snow Inc, Healthy Mother Healthy Child, Cairo, Egypt
来源：
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 2006年 / 94卷 / 02期
关键词：
postpartum hemorrhage; misoprostol; active management of the third stage of labor;
D O I：
10.1016/j.ijgo.2006.05.027
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective: To compare current practices for the active management of the third stage of labor (AMTSL) with the use of 600 mu g of oral misoprostol. Methods: An operations research study was designed to compare blood toss with current AMTSL practices and misoprostol use. Results: Women in the misoprostol group were less likely to bleed 500 ml or more (adjusted odds ratio, 0.30; 95% confidence interval, 0.16-0.56) compared with those in the current practices group. In the current practices group 73% women required interventions because of postpartum hemorrhage, compared with 11% in the misoprostot group. Conclusion: In situations where oxytocin and or ergometrine are not consistently and appropriately used during third stage of labor, misoprostol should be considered for inclusion in the AMTSL protocol. (c) 2006 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：149 / 155
页数：7
相关论文
共 25 条
[1]  
[Anonymous], COCHRANE DATABASE SY
[2]   Misoprostol for women's health: A review [J].
Blanchard, K ;
Clark, S ;
Winikoff, B ;
Gaines, G ;
Kabani, G ;
Shannon, C .
OBSTETRICS AND GYNECOLOGY, 2002, 99 (02) :316-332
[3]   Misoprostol for prevention of postpartum hemorrhage [J].
Bugalho, A ;
Daniel, A ;
Faúndes, A ;
Cunha, M .
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2001, 73 (01) :1-6
[4]   Oral misoprostol for the third stage of labor:: A randomized controlled trial [J].
Çaliskan, E ;
Dilbaz, B ;
Meydanli, MM ;
Öztürk, N ;
Narin, MA ;
Haberal, A .
OBSTETRICS AND GYNECOLOGY, 2003, 101 (05) :921-928
[5]  
Campbell C, 2005, B WORLD HEALTH ORGAN, V83, P462
[6]   Management of the third stage of labor in an Egyptian teaching hospital [J].
Cherine, M ;
Khalil, K ;
Hassanein, N ;
Sholkamy, H ;
Breebaart, M ;
Elnoury, A .
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2004, 87 (01) :54-58
[7]   The misoprostol third stage of labour study: a randomised controlled comparison between orally administered misoprostol and standard management [J].
El-Refaey, H ;
Nooh, R ;
O'Brien, P ;
Abdalla, M ;
Geary, M ;
Walder, J ;
Rodeck, C .
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2000, 107 (09) :1104-1110
[8]   Use of oral misoprostol in the prevention of postpartum haemorrhage [J].
ElRefaey, H ;
OBrien, P ;
Morafa, W ;
Walder, J ;
Rodeck, C .
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1997, 104 (03) :336-339
[9]   Rectal misoprostol versus intravenous oxytocin for the prevention of postpartum hemorrhage after vaginal delivery [J].
Gerstenfeld, TS ;
Wing, DA .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2001, 185 (04) :878-882
[10]   WHO multicentre randomised trial of misoprostol in the management of the third stage of labour [J].
Gülmezoglu, AM ;
Villar, J ;
Ngoc, NTN ;
Piaggio, G ;
Carroli, G ;
Adetoro, L ;
Abdel-Aleem, H ;
Cheng, LN ;
Hofmeyr, GJ ;
Lumbiganon, P ;
Unger, C ;
Prendiville, W ;
Pinol, A ;
Elbourne, D ;
El-Refaey, H ;
Schulz, KF .
LANCET, 2001, 358 (9283) :689-695
123