Performance of Alzheimer's disease patients in judging word relatedness

被引：15

作者：

Bayles, KA ^{[1
]}

Tomoeda, CK ^{[1
]}

Cruz, RF ^{[1
]}

机构：

[1] Univ Arizona, Dept Speech & Hearing Sci, Natl Ctr Neurogen Commun Disorders, Tucson, AZ 85721 USA

来源：

JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY | 1999年 / 5卷 / 07期

关键词：

Alzheimer's disease; semantic memory; conceptual knowledge; semantic relations;

D O I：

10.1017/S1355617799577096

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Sixty individuals with probable Alzheimer's disease (AD) and 48 normal elders were given a task in which they had to judge the relatedness of concepts as a means of evaluating semantic memory. Very mild AD patients performed similarly to normal elders. Mild AD patients were significantly inferior in performance to normals but the pattern of their performance did not suggest a loss of conceptual knowledge. Moderate AD patients were significantly inferior in performance to mild AD patients, and 8 moderate AD patients (compared to 1 mild AD patient) were unable to do the task. The pattern of performance of moderate patients suggests that conceptual knowledge may degrade and ultimately be lost.

引用

页码：668 / 675

页数：8

共 18 条

[1] ALZHEIMERS-DISEASE EFFECTS ON SEMANTIC MEMORY - LOSS OF STRUCTURE OR IMPAIRED PROCESSING [J].