A cross-sectional analysis of physical activity and obesity indicators in European participants of the EPIC-PANACEA study

被引:74
作者
Besson, H. [1 ,2 ]
Ekelund, U. [1 ]
Luan, J. [1 ]
May, A. M. [2 ,3 ]
Sharp, S. [1 ]
Travier, N. [4 ]
Agudo, A. [4 ]
Slimani, N. [5 ]
Rinaldi, S. [5 ]
Jenab, M. [6 ]
Norat, T. [7 ]
Mouw, T. [7 ]
Rohrmann, S. [8 ]
Kaaks, R. [8 ]
Bergmann, M. [9 ]
Boeing, H. [9 ]
Clavel-Chapelon, F. [10 ]
Boutron-Ruault, M. C. [10 ]
Overvad, K. [11 ,12 ]
Andreasen, E. L. [13 ]
Johnsen, N. Fons [14 ]
Halkjaer, J. [14 ]
Gonzalez, C. [4 ]
Rodriguez, L. [15 ]
Sanchez, M. J. [16 ,17 ]
Arriola, L. [18 ]
Barricarte, A. [19 ]
Navarro, C. [20 ]
Key, T. J. [21 ]
Spencer, E. A. [21 ]
Orfanos, P. [22 ,24 ]
Naska, A. [22 ,24 ]
Trichopoulou, A. [22 ,24 ]
Manjer, J. [23 ]
Wirfaelt, E. [25 ]
Lund, E. [26 ]
Palli, D. [27 ]
Agnoli, C. [28 ]
Vineis, P. [7 ,29 ]
Panico, S. [30 ]
Tumino, R. [31 ]
Bueno-de-Mesquita, H. B. [3 ]
van den Berg, S. W. [3 ]
Odysseos, A. D. [32 ]
Riboli, E. [7 ]
Wareham, N. J. [1 ]
Peeters, P. H. [2 ,7 ]
机构
[1] Inst Metab Sci, Epidemiol Unit, MRC, Cambridge CB2 0QQ, England
[2] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands
[3] Natl Inst Publ Hlth & Environm RIVM, Ctr Nutr & Hlth, Bilthoven, Netherlands
[4] May Catalan Inst Oncol IDIBELL, Unit Nutr Environm & Canc, Barcelona, Spain
[5] Int Agcy Res Canc, Epidemiol Methods & Support Grp, F-69372 Lyon, France
[6] Int Agcy Res Canc, Lifestyle Environm & Canc Grp, F-69372 Lyon, France
[7] Univ London Imperial Coll Sci Technol & Med, Div Epidemiol Publ Hlth & Primary Care, London, England
[8] German Canc Res Ctr, Div Canc Epidemiol, Nutr Epidemiol Unit, D-6900 Heidelberg, Germany
[9] German Inst Human Nutr Potsdam Rehbrucke, Dept Epidemiol, Nuthetal, Germany
[10] Inst Gustave Roussy, INSERM, ERI Nutr Hormones & Canc 20, F-94805 Villejuif, France
[11] Aarhus Univ Hosp, Dept Cardiol, Aalborg, Denmark
[12] Aarhus Univ Hosp, Dept Clin Epidemiol, Aalborg, Denmark
[13] Aarhus Univ Hosp, Dept Occupat Therapy & Physiotherapy, Aalborg, Denmark
[14] Danish Canc Soc, Inst Canc Epidemiol, Copenhagen, Denmark
[15] Hlth Directorate Asturias, Publ Hlth Informat Sect, Populat Hlth Serv, Oviedo, Spain
[16] CIBERESP, Granada, Spain
[17] Granada Canc Registry, Andalusian Sch Publ Hlth, Granada, Spain
[18] CIBERESP, Publ Hlth Div Gipuzkoa, San Sebastian, Spain
[19] Inst Publ Hlth Navarra, Epidemiol Prevent & Promot Hlth Serv, Pamplona, Spain
[20] CIBERESP, Murcia Hlth Council, Dept Epidemiol, Murcia, Spain
[21] Univ Oxford, Canc Res UK, Epidemiol Unit, Oxford, England
[22] Univ Athens, Sch Med, Dept Hyg & Epidemiol, Athens, Greece
[23] Malmo Univ Hosp, Dept Surg, Malmo, Sweden
[24] Hellen Hlth Fdn, Athens, Greece
[25] Lund Univ, Dept Clin Sci, Malmo, Sweden
[26] Univ Tromso, Inst Community Med, Tromso, Norway
[27] ISPO Canc Res & Prevent Inst, Mol & Nutr Epidemiol Unit, Florence, Italy
[28] Ist Nazl Tumori, Fondaz IRCCS, Nutr Epidemiol Unit, I-20133 Milan, Italy
[29] Univ Turin, Dept Biomed Sci & Human Oncol, I-10124 Turin, Italy
[30] Univ Naples Federico II, Dept Clin & Expt Med, Naples, Italy
[31] Azienda Osped Civile MP Arezzo, Canc Registry, Ragusa, Italy
[32] EPOS IASIS, R&D, Biomed Res, Nicosia, Cyprus
基金
英国医学研究理事会;
关键词
physical activity; BMI; waist circumference; cross-sectional analysis; Europe; BODY-COMPOSITION; ENERGY-EXPENDITURE; FAT DISTRIBUTION; LEISURE-TIME; WEIGHT-GAIN; CANCER; OVERWEIGHT; ADIPOSITY; VALIDITY; HEALTH;
D O I
10.1038/ijo.2009.25
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: Cross-sectional data suggest a strong association between low levels of physical activity and obesity. The EPIC-PANACEA ( European Prospective Investigation into Cancer-Physical Activity, Nutrition, Alcohol, Cessation of Smoking, Eating out of home And obesity) project was designed to investigate the associations between physical activity and body mass index (BMI) and waist circumference based on individual data collected across nine European countries. Methods: In the European Prospective Investigation into Cancer and Nutrition ( EPIC), 519 931 volunteers were recruited between 1992 and 2000, of whom 405 819 had data on main variables of interest. Height, body weight and waist circumference were measured using standardized procedures. Physical activity was assessed using a validated four-category index reflecting a self-reported usual activity during work and leisure time. The associations between physical activity and BMI and waist circumference were estimated using multilevel mixed effects linear regression models, adjusted for age, total energy intake, smoking status, alcohol consumption and educational level. Results: A total of 125 629 men and 280 190 women with a mean age of 52.9 (s.d. 9.7) and 51.5 (s.d. 10.0) years, respectively were included. The mean BMI was 26.6 kg/m(2) (s.d. 3.6) in men and 25.0 kg/m(2) (s.d. 4.5) in women. Fifty percent of men and 30% of women were categorized as being active or moderately active. A one-category difference in the physical activity index was inversely associated with a difference of 0.18 kg/m(2) in the mean BMI (95% confidence interval, CI, 0.11, 0.24) and 1.04-cm (95% CI 0.82, 1.26) difference in waist circumference in men. The equivalent figures for women were 0.31 kg/m(2) (95% CI 0.23, 0.38) and 0.90 cm ( 95% CI 0.71, 1.08), respectively. Conclusions: Physical activity is inversely associated with both BMI and waist circumference across nine European countries. Although we cannot interpret the association causally, our results were observed in a large and diverse cohort independently from many potential confounders.
引用
收藏
页码:497 / 506
页数:10
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