Signal sequence recognition and protein targeting

被引：71

作者：

Stroud, RM ^{[1
]}

Walter, P

机构：

[1] Univ Calif San Francisco, Sch Med, Dept Biochem & Biophys S960, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Sch Med, Dept Biochem & Biophys, Howard Hughes Med Inst, San Francisco, CA 94143 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1999年 / 9卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-440X(99)00040-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Intracellular traffic is often controlled not by highways, but by handshakes and partner introductions within a cellular network. Recently determined structures suggest how signal sequences are recognized and how the GTP affinities of the signal recognition particle and its receptor are coupled to the targeting of ribosomes to translocational membrane pores. The structure of signal peptidase suggests how it releases functional proteins.

引用

页码：754 / 759

页数：6

共 34 条

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