Rapidly progressive dementia due to Mycobacterium neoaurum meningoencephalitis

被引:30
作者
Heckman, GA
Hawkins, C
Morris, A
Burrows, LL
Bergeron, C
机构
[1] Freeport Hlth Ctr, Kitchener, ON, Canada
[2] McMaster Univ, Hamilton, ON, Canada
[3] Univ Toronto, Toronto, ON, Canada
[4] Toronto Western Hosp, Toronto, ON M5T 2S8, Canada
关键词
D O I
10.3201/eid1005.030711
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Dementia developed in a patient with widespread neurologic manifestations; she died within 5 months. Pathologic findings showed granulomatous inflammation with caseation necrosis, foreign body-type giant cells, and proliferative endarteritis with vascular occlusions. Broad-range polymerase chain reaction identified Mycobacterium neoaurum as the possible pathogen. Central nervous system infection by M. neoaurum may result in rapidly progressive dementia.
引用
收藏
页码:924 / 927
页数:4
相关论文
共 21 条
[1]   Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].
Altschul, SF ;
Madden, TL ;
Schaffer, AA ;
Zhang, JH ;
Zhang, Z ;
Miller, W ;
Lipman, DJ .
NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402
[2]  
Becker Marissa L, 2003, Can J Infect Dis, V14, P45
[3]   CREUTZFELDT-JAKOB DISEASE - CLINICAL ANALYSIS OF A CONSECUTIVE SERIES OF 230 NEUROPATHOLOGICALLY VERIFIED CASES [J].
BROWN, P ;
CATHALA, F ;
CASTAIGNE, P ;
GAJDUSEK, DC .
ANNALS OF NEUROLOGY, 1986, 20 (05) :597-602
[4]   CSF detection of the 14-3-3 protein in unselected patients with dementia [J].
Burkhard, PR ;
Sanchez, JC ;
Landis, T ;
Hochstrasser, DF .
NEUROLOGY, 2001, 56 (11) :1528-1533
[5]   BACTEREMIA CAUSED BY MYCOBACTERIUM-NEOAURUM [J].
DAVISON, MB ;
MCCORMACK, JG ;
BLACKLOCK, ZM ;
DAWSON, DJ ;
TILSE, MH ;
CRIMMINS, FB .
JOURNAL OF CLINICAL MICROBIOLOGY, 1988, 26 (04) :762-764
[6]   Mycobacterium neoaurum -: An unusual cause of infection of vascular catheters:: Case report and review [J].
George, SL ;
Schlesinger, LS .
CLINICAL INFECTIOUS DISEASES, 1999, 28 (03) :682-683
[7]   Detection of eubacteria in interstitial cystitis by 16S rDNA amplification [J].
Heritz, DM ;
Lacroix, JMY ;
Batra, SD ;
Jarvi, KA ;
Beheshti, B ;
Mittelman, MW .
JOURNAL OF UROLOGY, 1997, 158 (06) :2291-2295
[8]   MYCOBACTERIUM NEOAURUM INFECTION OF A HICKMAN CATHETER IN AN IMMUNOSUPPRESSED PATIENT [J].
HOLLAND, DJ ;
CHEN, SCA ;
CHEW, WWK ;
GILBERT, GL .
CLINICAL INFECTIOUS DISEASES, 1994, 18 (06) :1002-1003
[9]   The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies [J].
Hsich, G ;
Kinney, K ;
Gibbs, CJ ;
Lee, KH ;
Harrington, MG .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (13) :924-930
[10]   14-3-3 testing in diagnosing Creutzfeldt-Jakob disease - A prospective study in 112 patients [J].
Lemstra, AW ;
van Meegen, MT ;
Vreyling, JP ;
Meijerink, PHS ;
Jansen, GH ;
Bulk, S ;
Baas, F ;
van Gool, WA .
NEUROLOGY, 2000, 55 (04) :514-516