Minimizing the Risk of Posttransplant Malignancy

被引：34

作者：

Campistol, Josep M. ^{[1
]}

机构：

[1] Univ Barcelona, Dept Nephrol & Renal Transplantat, Inst Clin, Hosp Clin, Barcelona, Spain

来源：

TRANSPLANTATION | 2009年 / 87卷 / 08期

关键词：

KIDNEY-TRANSPLANTATION; CANCER; SIROLIMUS; INHIBITORS; CONVERSION; THERAPY;

D O I：

10.1097/TP.0b013e3181a07a57

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Nowadays cancer represents the second main cause of death in renal transplant patients with normal function of the graft. The incidence is 10 to 20 times higher than normal population. Calcineurin inhibitor therapy contributes to the increase in the development of neoplasia. Important evidence could bring a preventive effect of mammalian target of rapamycin in skin cancer, Kaposi's sarcoma, and renal cell carcinoma.

引用

页码：S19 / S22

页数：4

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