fMRI of the lumbar spinal cord during a lower limb motor task

被引:55
作者
Kornelsen, J
Stroman, PW
机构
[1] Univ Manitoba, Dept Physiol, Winnipeg, MB, Canada
[2] Natl Res Council Canada, Inst Biodiagnost, Winnipeg, MB R3B 1Y6, Canada
关键词
spinal fMRI; spinal cord; motor; human; imaging;
D O I
10.1002/mrm.20157
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
This study applied spinal fMRI to the lumbar spinal cord during lower limb motor activity. During active ankle movement, activity was detected in the lumbar spinal cord motor areas and sensory areas bilaterally. During passive ankle movement, activity was detected in the motor and sensory areas in lower lumbar spinal cord segments and motor activity in higher lumbar spinal cord segments. Spinal fMRI detects patterns of activity consistent with known physiology and can be used to reliably assess activity in the lumbar spinal cord during lower limb motor stimulation. This study affirms spinal fMRI as an effective tool for assessing spinal cord function and increases its potential as a clinical tool.
引用
收藏
页码:411 / 414
页数:4
相关论文
共 13 条
[1]   Differential projections of thermoreceptive and nociceptive lamina I trigeminothalamic and spinothalamic neurons in the cat [J].
Craig, AD ;
Dostrovsky, JO .
JOURNAL OF NEUROPHYSIOLOGY, 2001, 86 (02) :856-870
[2]   Neurophysiological investigation of the basis of the fMRI signal [J].
Logothetis, NK ;
Pauls, J ;
Augath, M ;
Trinath, T ;
Oeltermann, A .
NATURE, 2001, 412 (6843) :150-157
[3]  
MENON RS, 1992, INVEST RADIOL, V27, P47
[4]   BRAIN MAGNETIC-RESONANCE-IMAGING WITH CONTRAST DEPENDENT ON BLOOD OXYGENATION [J].
OGAWA, S ;
LEE, TM ;
KAY, AR ;
TANK, DW .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (24) :9868-9872
[5]   INTRINSIC SIGNAL CHANGES ACCOMPANYING SENSORY STIMULATION - FUNCTIONAL BRAIN MAPPING WITH MAGNETIC-RESONANCE-IMAGING [J].
OGAWA, S ;
TANK, DW ;
MENON, R ;
ELLERMANN, JM ;
KIM, SG ;
MERKLE, H ;
UGURBIL, K .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (13) :5951-5955
[6]   Mapping of neuronal function in the healthy and injured human spinal cord with spinal fMRI [J].
Stroman, PW ;
Tomanek, B ;
Krause, V ;
Frankenstein, UN ;
Malisza, KL .
NEUROIMAGE, 2002, 17 (04) :1854-1860
[7]   Noninvasive assessment of the injured human spinal cord by means of functional magnetic resonance imaging [J].
Stroman, PW ;
Kornelsen, J ;
Bergman, A ;
Krause, V ;
Ethans, K ;
Malisza, KL ;
Tomanek, B .
SPINAL CORD, 2004, 42 (02) :59-66
[8]   Functional magnetic resonance imaging at 0.2 Tesla [J].
Stroman, PW ;
Malisza, KL ;
Onu, M .
NEUROIMAGE, 2003, 20 (02) :1210-1214
[9]   Functional magnetic resonance imaging of the human cervical spinal cord with stimulation of different sensory dermatomes [J].
Stroman, PW ;
Krause, V ;
Malisza, KL ;
Frankenstein, UN ;
Tomanek, B .
MAGNETIC RESONANCE IMAGING, 2002, 20 (01) :1-6
[10]   Extravascular proton-density changes as a Non-BOLD component of contrast in fMRI of the human spinal cord [J].
Stroman, PW ;
Krause, V ;
Malisza, KL ;
Frankenstein, UN ;
Tomanek, B .
MAGNETIC RESONANCE IN MEDICINE, 2002, 48 (01) :122-127