First Australian isolation of epidemic Clostridium difficile PCR ribotype 027

被引：58

作者：

Riley, Thomas V. ^{[1
,2
]}

Thean, Sarah ^{[2
]}

Hool, Graham

Golledge, Clayton L. ^{[2
]}

机构：

[1] Univ Western Australia, Perth, WA 6009, Australia

[2] Queen Elizabeth II Med Ctr, PathWest Lab Med WA, Div Microbiol & Infect Dis, Perth, WA, Australia

来源：

MEDICAL JOURNAL OF AUSTRALIA | 2009年 / 190卷 / 12期

关键词：

DIARRHEA; STRAINS; TOXIN;

D O I：

10.5694/j.1326-5377.2009.tb02644.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report the first isolation in Australia of a hypervirulent epidemic strain of Clostridium difficile, PCR ribotype 027. it was isolated from a 43-year-old woman with a permanent ileostomy, who appears to have been infected while travelling in the United States. The isolate was positive for toxin A, toxin B and binary toxin, and resistant to fluoroquinolone antimicrobials, and had characteristic deletions in the tcdC gene. All diagnostic laboratories and health care facilities in Australia should now be on high alert for this organism. (MJA 2009, 190: 706-708)

引用

页码：706 / 708

页数：3

共 14 条

[1] CLOSTRIDIUM-DIFFICILE - CLINICAL CONSIDERATIONS [J].

BARTLETT, JG .

REVIEWS OF INFECTIOUS DISEASES, 1990, 12 :S243-S251

[2]

*CDCP, 2008, STAT BI NAP1 027 STR

[3] The Vexed Relationship Between Clostridium Difficile and Inflammatory Bowel Disease: An Assessment of Carriage in an Outpatient Setting Among Patients in Remission [J].

Clayton, Evelyn M. ;

Rea, Mary C. ;

Shanahan, Fergus ;

Quigley, Eamonn M. M. ;

Kiely, Barry ;

Hill, Colin ;

Ross, R. Paul .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2009, 104 (05) :1162-1169

[4] tcdC genotypes associated with severe TcdC truncation in an epidemic clone and other strains of Clostridium difficile [J].

Curry, Scott R. ;

Marsh, Jane W. ;

Muto, Carlene A. ;

O'Leary, Mary M. ;

Pasculle, A. William ;

Harrison, Lee H. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2007, 45 (01) :215-221

[5] CLOSTRIDIUM-DIFFICILE-ASSOCIATED DIARRHEA AFTER DOXYCYCLINE MALARIA PROPHYLAXIS [J].

GOLLEDGE, CL ;

RILEY, TV .

LANCET, 1995, 345 (8961) :1377-1378

[6]

Indra A, 2006, EUROSURVEILLANCE, V11

[7] Identification of toxin A-negative, toxin B-positive Clostridium difficile by PCR [J].

Kato, H ;

Kato, N ;

Watanabe, K ;

Iwai, N ;

Nakamura, H ;

Yamamoto, T ;

Suzuki, K ;

Kim, SM ;

Chong, Y ;

Wasito, EB .

JOURNAL OF CLINICAL MICROBIOLOGY, 1998, 36 (08) :2178-2182

[8] Spectrum of Clostridium difficile infections outside health care facilities [J].

Kuijper, Ed J. ;

van Dissel, Jaap T. .

CANADIAN MEDICAL ASSOCIATION JOURNAL, 2008, 179 (08) :747-748

[9] Molecular analysis of Clostridium difficile PCR ribotype 027 isolates from Eastern and Western Canada [J].

MacCannell, Duncan R. ;

Louie, Thomas J. ;

Gregson, Dan B. ;

Laverdiere, Michel ;

Labbe, Annie-Claude ;

Laing, Felicia ;

Henwick, Scott .

JOURNAL OF CLINICAL MICROBIOLOGY, 2006, 44 (06) :2147-2152

[10] Clostridium difficile-associated diarrhea after antibiotic treatment for traveler's diarrhea [J].

Norman, Francesca F. ;

Perez-Molina, J. ;

Perez de Ayala, A. ;

Jimenez, B. C. ;

Navarro, M. ;

Lopez-Velez, R. .

CLINICAL INFECTIOUS DISEASES, 2008, 46 (07) :1060-1063

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