Why aging T cells fail: Implications for vaccination

被引：127

作者：

Haynes, Laura ^{[1
]}

Swain, Susan L. ^{[1
]}

机构：

[1] Trudeau Inst Inc, Saranac Lake, NY 12983 USA

来源：

IMMUNITY | 2006年 / 24卷 / 06期

关键词：

D O I：

10.1016/j.immuni.2006.06.003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The decline in CD4(+) T cell function with aging contributes to reduced vaccine efficacy. In this commentary, we discuss the factors leading to age-related changes in T cell function and propose how they may be overcome to enhance vaccine efficacy for the elderly.

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收藏

页码：663 / 666

页数：4

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