Modification of biochemical pathways in industrial yeasts

被引:23
作者
Hansen, J [1 ]
KiellandBrandt, MC [1 ]
机构
[1] CARLSBERG LAB, DEPT YEAST GENET, DK-2500 COPENHAGEN, DENMARK
关键词
industrial yeasts; Saccharomyces cerevisiae; Saccharomyces carlsbergensis; metabolic engineering; alloploid; species hybrid; diacetyl; terpenes; lagering; beer; wine; sulfite; hydrogen sulfide; genome sequencing; aroma; higher alcohols; aromatic amino acids; branched-chain amino acids; sulfur-containing amino acids;
D O I
10.1016/0168-1656(96)01523-4
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Yeasts have many applications in industrial food and beverage production. While these uses are often of ancient origin, modern demands for control of the amounts of process-derived compounds and for cost-effective processing can make it desirable to modify metabolic pathways of production yeasts. While the genetics of standard laboratory strains of Saccharomyces cerevisiae are well described, industrial strains and species are less characterized, and many of them have a complicated genetic constitution. Nevertheless, their biochemical pathways can be modified, and the knowledge becoming available on the physiology of genetic reference strains of S. cerevisiae is a great help in directing the modifications of the industrial yeasts towards practical goals.
引用
收藏
页码:1 / 12
页数:12
相关论文
共 75 条
[1]  
[Anonymous], METHOD ENZYMOL
[2]   ENHANCED FORMATION OF 3-(METHYLTHIO)-1-PROPANOL IN A SALT-TOLERANT YEAST, ZYGOSACCHAROMYCES-ROUXII, DUE TO DEFICIENCY OF S-ADENOSYLMETHIONINE-SYNTHASE [J].
AOKI, T ;
UCHIDA, K .
AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1991, 55 (08) :2113-2116
[3]  
ASHIDA S, 1987, AGR BIOL CHEM TOKYO, V51, P2061
[4]   THE TAXONOMY OF THE GENUS SACCHAROMYCES MEYEN EX REESS - A SHORT REVIEW FOR NON-TAXONOMISTS [J].
BARNETT, JA .
YEAST, 1992, 8 (01) :1-23
[5]   CHROMOSOMAL INTEGRATION AND EXPRESSION OF 2 BACTERIAL ALPHA-ACETOLACTATE DECARBOXYLASE GENES IN BREWERS-YEAST [J].
BLOMQVIST, K ;
SUIHKO, ML ;
KNOWLES, J ;
PENTTILA, M .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1991, 57 (10) :2796-2803
[6]  
BRENNER MW, 1970, MBAA TECH Q, V7, P150
[7]  
Brewer J. D., 1980, In 'Proceedings of the Sixteenth Convention' [see FSTA (1981) 13 8H1234]., P155
[8]   CLONING AND ANALYSIS OF 2 ALLELES OF THE ILV3 GENE FROM SACCHAROMYCES CARLSBERGENSIS [J].
CASEY, GP .
CARLSBERG RESEARCH COMMUNICATIONS, 1986, 51 (05) :327-341
[9]  
CASEY GP, 1986, CARLSBERG RES COMMUN, V51, P343, DOI 10.1007/BF02907166
[10]   ISOLATION AND PROPERTIES OF YEAST MUTANTS AFFECTED IN FARNESYL DIPHOSPHATE SYNTHETASE [J].
CHAMBON, C ;
LADEVEZE, V ;
OULMOUDEN, A ;
SERVOUSE, M ;
KARST, F .
CURRENT GENETICS, 1990, 18 (01) :41-46