INFLAMMATION IL-36 has proinflammatory effects in skin but not in joints

被引：43

作者：

Dietrich, Damien ^{[1
]}

Gabay, Cem ^{[1
]}

机构：

[1] Univ Hosp Geneva, Div Rheumatol, CH-1211 Geneva 14, Switzerland

来源：

NATURE REVIEWS RHEUMATOLOGY | 2014年 / 10卷 / 11期

关键词：

T-CELLS; ARTHRITIS;

D O I：

10.1038/nrrheum.2014.156

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Given the known involvement of IL 36 in psoriasis it might be surprising that the latest mouse models show that inhibiting IL-36 signalling does not alter the course of inflammatory arthritis. Can we now add IL-36 to the list of inflammatory mediators that are not viable DMARD targets? © 2014 Macmillan Publishers Limited. All rights reserved.

引用

页码：639 / 640

页数：2

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