Ion channels: doing hard chemistry with hard ions

被引：37

作者：

Miller, C ^{[1
]}

机构：

[1] Brandeis Univ, Howard Hughes Med Inst, Dept Biochem, Waltham, MA 02254 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2000年 / 4卷 / 02期

关键词：

D O I：

10.1016/S1367-5931(99)00068-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

For years, the mechanisms and structural underpinnings of ion selectivity by ion channel proteins have been inferred by indirect experiments. The recently determined structure of a K+ channel has put flesh on these bones, revealing the coordination chemistry responsible for the unusual combination of high selectivity and high transport rates in ion channels.

引用

页码：148 / 151

页数：4

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