(-)-Wistarin from the marine sponge Ircinia sp.:: the first case of enantiomeric sesterterpenes

被引：18

作者：

Fontana, A

Fakhr, I

Mollo, E

Cimino, G

机构：

[1] CNR, Ist Chim Mol Interesse Biol, I-80072 Arco Felice, Na, Italy

[2] Natl Res Ctr, Cairo, Egypt

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 20期

关键词：

D O I：

10.1016/S0957-4166(99)00406-1

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The sestertepene (-)-wistarin has been isolated from a Red Sea sponge of the genus Ircinia. This metabolite is the enantiomer of (+)-wistarin, a tetracyclic metabolite previously isolated from the sponge Ircinia wistarii. The enantiomeric relationship was proved by comparison of the CD spectrum of (-)-wistarin with that of a synthetic sample of the (+)-isomer. A hypothetical biosynthesis of (-)-wistarin is discussed starting from a putative linear precursor. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：3869 / 3872

页数：4

共 10 条

[1]

CIMINO G, 1975, TETRAHEDRON LETT, P1425

[2] Ircinianin sulfate from the marine sponge Ircinia (Psammocinia) wistarii [J].