The Effect of the Kampo Medicine Yokukansan on Preoperative Anxiety and Sedation Levels

被引：18

作者：

Arai, Young-Chang ^{[1
,2
]}

Kawanishi, Jun ^{[1
]}

Sakakima, Yoshikazu ^{[1
]}

Sueoka, Satoshi ^{[1
]}

Ito, Akihiro ^{[1
]}

Tawada, Yusuke ^{[1
]}

Maruyama, Yuki ^{[1
]}

Banno, Shinya ^{[1
]}

Takayama, Hitomi ^{[1
]}

Nishihara, Makoto ^{[2
]}

Kawai, Takashi ^{[2
]}

Ikemoto, Tatsunori ^{[2
]}

机构：

[1] Toki Gen Hosp, Dept Surg, Gifu 5095193, Japan

[2] Aichi Med Univ, Sch Med, Ctr Multidisciplinary Pain, Nagakute, Aichi 4801195, Japan

来源：

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2014年 / 2014卷

关键词：

SALIVARY AMYLASE ACTIVITY; JAPANESE MEDICINE; ANESTHESIA; SYMPTOMS; DEMENTIA; MONITOR;

D O I：

10.1155/2014/965045

中图分类号：

R [医药、卫生];

学科分类号：

100218 [急诊医学];

摘要：

Background. Preoperative anxiety can lead to unfavorable physiological response such as tachycardia and hypertension. Prevention of preoperative anxiety improves surgical outcome and decreases inpatient stay. Yokukansan is one of prescriptions in Kampo, traditional Japanese herbal medicine, and is known to exert anxiolytic effects. The aim of the present study was to compare the effects of diazepam and Yokukansan on preoperative anxiety, salivary amylase activity, and sedation levels. Methods. Seventy American Society of Anesthesiologists physical status I or II patients presenting for hemicolectomy under general anesthesia combined with epidural anesthesia were enrolled. The Diazepam group received diazepam 5mg orally and the Yokukansan group received Yokukansan 2.5 g orally. Results. Although levels of anxiety and salivary amylase activity were not different between the two groups, the modified Observer's Assessment of Alertness/Sedation Scale of the Yokukansan group was significantly higher compared to that of the Diazepam group. Conclusion. Yokukansan alleviated preoperative anxiety without undesirable sedation, when compared with diazepam.

引用

页数：4

共 16 条

[1]

Intra-operative natural sound decreases salivary amylase activity of patients undergoing inguinal hernia repair under epidural anesthesia [J].

Arai, Y. -C. P. ;

Sakakibara, S. ;

Ito, A. ;

Ohshima, K. ;

Sakakibara, T. ;

Nishi, T. ;

Hibino, S. ;

Niwa, S. ;

Kuniyoshi, K. .

ACTA ANAESTHESIOLOGICA SCANDINAVICA, 2008, 52 (07) :987-990

[2]

Kampo Diagnostic Procedure, Fuku shin, Could Be a Useful Diagnostic Tool for Psychopathological Patients Suffering from Chronic Pain [J].

Arai, Young-Chang P. ;

Nishihara, Makoto ;

Inoue, Shinsuke ;

Makino, Izumi .

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2013, 2013

[3]

Prediction of depth of sedation and anaesthesia by the Narcotrend™ EEG monitor [J].

Bauerle, K ;

Greim, CA ;

Schroth, M ;

Geisselbrecht, M ;

Köbler, A ;

Roewer, N .

BRITISH JOURNAL OF ANAESTHESIA, 2004, 92 (06) :841-845

[4]

Carroll Jennifer K, 2012, Br J Nurs, V21, P479

[5]

Anaesthetists' and surgeons' estimation of preoperative anxiety by patients submitted for elective surgery in a university hospital [J].

Fekrat, E ;

Sahin, A ;

Yazici, KM ;

Aypar, U .

EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2006, 23 (03) :227-233

[6]

New possibility of traditional Chinese and Japanese medicine as treatment for behavioral and psychiatric symptoms in dementia [J].

Kung, Fan-Chin ;

Ishii, Ryouhei ;

Liu, Hsing-Cheng ;

Takeda, Masatoshi .

CLINICAL INTERVENTIONS IN AGING, 2012, 7 :393-396

[7]

Intranasal dexmedetomidine following failed chloral hydrate sedation in children [J].

Li, B. L. ;

Yuen, V. M. ;

Song, X. R. ;

Ye, J. ;

Ni, J. ;

Huang, J. X. ;

Irwin, M. G. .

ANAESTHESIA, 2014, 69 (03) :240-244

[8]

Yokukansan in the treatment of behavioral and psychological symptoms of dementia: a systematic review and meta-analysis of randomized controlled trials [J].

Matsuda, Yuki ;

Kishi, Taro ;

Shibayama, Hiroto ;

Iwata, Nakao .

HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, 2013, 28 (01) :80-86

[9]

Usage and Attitudes of Physicians in Japan Concerning Traditional Japanese Medicine (Kampo Medicine): A Descriptive Evaluation of a Representative Questionnaire-Based Survey [J].

Moschik, E. C. ;

Mercado, C. ;

Yoshino, T. ;

Matsuura, K. ;

Watanabe, K. .

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2012, 2012

[10]

The relationship and influence of anxiety on postoperative pain in the coronary artery bypass graft patient [J].

Nelson, FV ;

Zimmerman, L ;

Barnason, S ;

Nieveen, J ;

Schmaderer, M .

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 1998, 15 (02) :102-109

← 1 2 →