Cortical reorganization after acute unilateral hearing loss traced by fMRI

被引：131

作者：

Bilecen, D

Seifritz, E

Radü, EW

Schmid, N

Wetzel, S

Probst, R

Scheffler, K

机构：

[1] Univ Basel, Dept Radiol, CH-4003 Basel, Switzerland

[2] Univ Basel, Dept Psychiat, CH-4003 Basel, Switzerland

[3] Univ Basel, Dept Otorhinolaryngol, CH-4003 Basel, Switzerland

[4] Univ Freiburg, Dept Diagnost Radiol, Sect Med Phys, D-7800 Freiburg, Germany

来源：

NEUROLOGY | 2000年 / 54卷 / 03期

关键词：

neuronal plasticity; fMRI; acoustic stimulation; auditory cortex;

D O I：

10.1212/WNL.54.3.765

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Unilateral acoustic stimulation produces a functional MRI (fMRI)-blood-oxygenation-level-dependent (BOLD) response mainly in the contralateral auditory cortex. In unilateral deaf patients, the BOLD response is bilateral. We studied a subject with sudden hearing loss after cochlear nerve resection before and repeatedly after surgery. During normal bilateral hearing, contralateral cortical BOLD responses were found. Progressing compensatory reorganization with bilateral representation of unilateral stimulation was detected over a period of approximately 1 year.

引用

页码：765 / 767

页数：3

共 10 条

[1] Single olivocochlear neurons in the guinea pig. I. Binaural facilitation of responses to high-level noise [J].