Measurements of gastric emptying of low- and high-nutrient liquids using 3D ultrasonography and scintigraphy in healthy subjects

被引:75
作者
Gentilcore, D.
Hausken, T.
Horowitz, M.
Jones, K. L.
机构
[1] Univ Adelaide, Royal Adelaide Hosp, Discipline Med, Adelaide, SA 5000, Australia
[2] Univ Bergen, Haukeland Univ Hosp, Inst Med, Div Gastroenterol, Bergen, Norway
关键词
gastric emptying; imaging; scintigraphy; three-dimensional; two-dimensional; ultrasound;
D O I
10.1111/j.1365-2982.2006.00830.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Scintigraphy represents the 'gold standard' for the measurement of gastric emptying. Recent studies suggest that three-dimensional (3D) ultrasonography may allow a precise measure of gastric emptying, given the capacity for accurate volume calculations of the stomach. The aim of this study was to compare measurements of gastric emptying of both low- and high-nutrient drinks by 3D ultrasonography with scintigraphy. Ten healthy young subjects (6M, 4F, age 23.5 +/- 1.5 years) were studied on 2 days. Concurrent measurements of gastric emptying by scintigraphy and 3D ultrasonography were performed after ingestion of 500 mL beef soup (12 kcal) or 300 ml dextrose (25% w/v) (314 kcal) labelled with 20 MBq Tc-99m-sulphur colloid. There was no significant difference between scintigraphic and ultrasonographic 50% emptying times (T50s) (soup: 27.7 +/- 4.8 min vs 23.8. +/- 4.8 min; dextrose: 122.2 +/- 13.3 min vs 131.9 +/- 10.2 min). There was a close correlation between scintigraphic and ultrasonographic T50s for both soup (r = 0.92, P = 0.0005) and dextrose (r = 0.88, P = 0.0007). For the T50s, the limits of agreement were -15.2 min and +8.1 min for the soup (mean difference -3.6 min) and -35.3 min and +47.6 min for dextrose (mean difference +6.2 min). 3D ultrasonography provides a valid measure of gastric emptying of liquid meals in healthy subjects.
引用
收藏
页码:1062 / 1068
页数:7
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