In search of an optimum dose escalation for narrowband UVB phototherapy:: Is it time to quit 20% increments?

被引：17

作者：

Boztepe, Gonca ^{[1
]}

Akinci, Hande ^{[1
]}

Sahin, Sedef ^{[1
]}

Karaduman, Aysen ^{[1
]}

Evans, Sibel Ersoy ^{[1
]}

Erkin, Guel ^{[1
]}

Atakan, Nilguen ^{[1
]}

Akan, Tuelin ^{[1
]}

Koelemen, Fikret ^{[1
]}

机构：

[1] Hacettepe Univ, Fac Med, Dept Dermatol, TR-06100 Ankara, Turkey

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2006年 / 55卷 / 02期

关键词：

D O I：

10.1016/j.jaad.2006.04.019

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 [皮肤病与性病学];

摘要：

Objectives: Our aim was to compare 20% with 10% to 5% incremental regimens in narrowband UVB phototherapy. Study patients: The study included patients with psoriasis (N = 191) with Fitzpatrick skin phototypes II and III. Results. Occurrence of erythema as well as maximum and cumulative doses were higher with 20% escalations, whereas response rates and time to response did not significantly differ. Limitations: The study was limited by its retrospective nature. Conclusion: A 5% or 10% incremental regimen may have similar therapeutic efficacy.

引用

页码：269 / 271

页数：3

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