Biomaterials in drug delivery and tissue engineering: One laboratory's experience

被引：551

作者：

Langer, R ^{[1
]}

机构：

[1] MIT, Dept Chem Engn, Cambridge, MA 02139 USA

来源：

ACCOUNTS OF CHEMICAL RESEARCH | 2000年 / 33卷 / 02期

关键词：

D O I：

10.1021/ar9800993

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This Account reviews our laboratory's research in biomaterials. In one area, drug delivery, we discuss the development of materials that are capable of releasing macromolecules such as proteins and peptides, intelligent delivery systems based on magnetism or microchip technology, new degradable materials such as polyanhydrides, and noninvasive approaches for delivering molecules through the skin and lungs. A second area, tissue engineering, is also discussed. New polymer systems for creating cartilage, blood vessels, nerves, and other tissues are examined.

引用

页码：94 / 101

页数：8

共 71 条

[21]

Hansbrough John F., 1992, Journal of Burn Care and Rehabilitation, V13, P519, DOI 10.1097/00004630-199209000-00004

[22]

Heller J., 1997, CONTROLLED DRUG DELI, P127

[23] DRUG-THERAPY - NICOTINE MEDICATIONS FOR SMOKING CESSATION [J].