Human performance: A role for the ACE genotype?

被引:92
作者
Jones, A
Montgomery, HE
Woods, DR [1 ]
机构
[1] Freeman Rd Hosp, Dept Med, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England
[2] UCL, Dept Cardiovasc Genet, Rayne Inst, London, England
来源
EXERCISE AND SPORT SCIENCES REVIEWS | 2002年 / 30卷 / 04期
关键词
angiotensin I-converting enzyme polymorphism; renin-angiotensin; athletic performance; exercise;
D O I
10.1097/00003677-200210000-00008
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
The I allele of the angiotensin I-converting enzyme (ACE) gene is associated with lower ACE activity and endurance performance; an excess occurs in elite distance runners, rowers, and mountaineers, perhaps secondary to enhanced muscle efficiency. Conversely, the D allele is association with training-related strength gain and elite power-oriented performance secondary to increased ACE and angiotensin 11, a growth factor.
引用
收藏
页码:184 / 190
页数:7
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