Creutzfeldt-Jakob disease presenting as corticobasal degeneration: a neurophysiological study

被引：11

作者：

Avanzino, L. ^{[1
]}

Marinelli, L. ^{[1
]}

Buccolieri, A. ^{[1
]}

Trompetto, C. ^{[1
]}

Abbruzzese, G. ^{[1
]}

机构：

[1] Univ Genoa, Dept Neurosci Ophthalmol & Genet, I-16132 Genoa, Italy

来源：

NEUROLOGICAL SCIENCES | 2006年 / 27卷 / 02期

关键词：

Creutzfeldt-Jakob disease; corticobasal degeneration; transcranial magnetic stimulation; transcallosal inhibition;

D O I：

10.1007/s10072-006-0611-1

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Creutzfeldt-Jakob disease (CJD) can occasionally present with a clinical picture resembling a corticobasal degeneration (CBD). Transcallosal inhibition, as tested by focal transcranial magnetic stimulation, is frequently absent or highly disrupted in CBD patients. We report a case of CJD presenting at the beginning of the disease as a CBD in which the ipsilateral silent period (iSP) was present and well detectable. This brief report shows that study of the iSP may be a useful diagnostic tool in order to differentiate CBD from syndromes presenting with similar clinical features.

引用

页码：118 / 121

页数：4

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