Highly stereoselective route to aldol products incorporating fluorine-containing methyl groups starting from a single D-glucose-derived intermediate

被引：20

作者：

Yamazaki, T

Hiraoka, S

Kitazume, T

机构：

[1] Department of Bioengineering, Tokyo Institute of Technology, Yokohama 226, Nagatsuta, Midori-ku

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 08期

关键词：

D O I：

10.1016/S0957-4166(97)00120-1

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Chiral aldol structures with fluorine modifications on a methyl group have been realized by utilization of the relatively rigid cyclic intermediates from the very common chiral pool compound, D-glucose, leading to attainment of the high diastereoselectivities as well as construction of differently fluorinated target materials from a single intermediate. (C) 1997 Elsevier Science Ltd.

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页码：1157 / 1160

页数：4

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