In vitro susceptibilities of zygomycetes to combinations of antimicrobial agents

被引：64

作者：

Dannaoui, E

Afeltra, J

Meis, JFGM

Verweij, PE

机构：

[1] Univ Med Ctr St Radboud, Dept Med Microbiol, NL-6500 HB Nijmegen, Netherlands

[2] Canisius Wilhelmina Hosp, Dept Med Microbiol & Infect Dis, NL-65000 GS Nijmegen, Netherlands

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 08期

关键词：

D O I：

10.1128/AAC.46.8.2708-2711.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Combinations of antimicrobial agents were tested against 35 strains of zygomycetes. The interaction between amphotericin B and rifampin was synergistic or additive. Flucytosine alone was inactive and, upon combination with amphotericin B, synergy was not achieved. The combination of amphotericin B with terbinafine was synergistic for 20% of strains, and the interaction between terbinafine and voriconazole was synergistic for 44% of strains. Antagonism was not observed.

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页码：2708 / 2711

页数：4

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