Carbon Nanotubes Carrying Cell-Adhesion Peptides do not Interfere with Neuronal Functionality

被引：55

作者：

Gaillard, Claire ^{[2
]}

Cellot, Giada ^{[1
]}

Li, Shouping ^{[2
]}

Toma, Francesca Maria ^{[3
,4
]}

Dumortier, Helene ^{[2
]}

Spalluto, Giampiero ^{[3
]}

Cacciari, Barbara ^{[5
]}

Prato, Maurizio ^{[3
]}

Ballerini, Laura ^{[1
]}

Bianco, Alberto ^{[2
]}

机构：

[1] Univ Trieste, Dipartimento Sci Vita, I-34127 Trieste, Italy

[2] CNRS, Inst Biol Mol & Cellulaire, UPR Immunol & Chim Therapeut 9021, F-67000 Strasbourg, France

[3] Univ Trieste, Dipartimento Sci Farmaceut, I-34127 Trieste, Italy

[4] SISSA Elettra NanoInnovat Lab Synchrotron, Trieste, Italy

[5] Univ Ferrara, Dept Pharmaceut Sci, I-44100 Ferrara, Italy

来源：

ADVANCED MATERIALS | 2009年 / 21卷 / 28期

关键词：

HIPPOCAMPAL-NEURONS; NEURITE OUTGROWTH; DRUG-DELIVERY; GROWTH; STIMULATION; BRAIN; BIOCOMPATIBILITY; NANOMEDICINES; CYTOTOXICITY; REGENERATION;

D O I：

10.1002/adma.200900050

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Water-soluble carbon nanotubes functionalized with cell-adhesion peptides do not affect the viability of different cell types, including Jurkat cells, splenocytes, and neurons. They also do not modify the neuronal morphology and basic functions, thus representing a promising candidate for the exploitation of novel drug-delivery systems or for designing a new generation of self-assembling nerve bridges.

引用

页码：2903 / +

页数：7

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