Intramolecular palladium-catalyzed aryl amination and aryl amidation

被引:248
作者
Wolfe, JP [1 ]
Rennels, RA [1 ]
Buchwald, SL [1 ]
机构
[1] MIT,DEPT CHEM,CAMBRIDGE,MA 02139
关键词
D O I
10.1016/0040-4020(96)00266-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Upon treatment with a palladium catalyst and a suitable base, aromatic halides undergo intramolecular substitution to form five, six, and seven-membered rings. In a similar fashion aryl halides with pendant amides or sulfonamides are cyclized to form five and six-membered rings. Copyright (C) 1996 Elsevier Science Ltd
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页码:7525 / 7546
页数:22
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