Optimization of BMD measurements to identify high risk groups for treatment - A test analysis

被引:97
作者
Johansson, H
Oden, A
Johnell, O
Jonsson, B
de Laet, C
Oglesby, A
McCloskey, EV
Kayan, K
Jalava, T
Kanis, JA [1 ]
机构
[1] Univ Sheffield, Sch Med, Ctr Metab Bone Dis, WHO Collaborating Ctr, Sheffield S10 2RX, S Yorkshire, England
[2] Lerias Clin Res, Helsinki, Finland
[3] Malmo Gen Hosp, Dept Orthopaed, S-21401 Malmo, Sweden
[4] Stockholm Sch Econ, Dept Econ, S-11383 Stockholm, Sweden
[5] Erasmus Univ, Sch Med, Dept Publ Hlth, Rotterdam, Netherlands
[6] Eli Lilly & Co, Indianapolis, IN 46285 USA
关键词
fracture possibility; BMD tests; intervention threshold;
D O I
10.1359/jbmr.2004.19.6.906
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The aim of this study was to optimize the use of BMD measurements in case finding strategies. The use of clinical risk factors with and without BMD was explored in a random sample of the Sheffield female population greater than or equal to75 years of age. The use of clinical risk factors alone could identify women well above or well below a threshold of fracture risk. BMD assessment can be confined to a minority of women (similar to20%) in whom the measurement aids in prognostication of fracture.
引用
收藏
页码:906 / 913
页数:8
相关论文
共 33 条
[1]   Screening for osteoporosis in postmenopausal women: Recommendations and rationale [J].
Berg, AO ;
Allan, JD ;
Frame, PS ;
Homer, CJ ;
Johnson, MS ;
Klein, JD ;
Lieu, TA ;
Mulrow, CD ;
Orleans, CT ;
Peipert, JF ;
Pender, NJ ;
Siu, AL ;
Teutsch, SM ;
Westhoff, C ;
Woolf, SH .
ANNALS OF INTERNAL MEDICINE, 2002, 137 (06) :526-528
[2]  
Black D, 2002, J BONE MINER RES, V17, pS474
[3]   Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures - Results from the fracture intervention trial [J].
Cummings, SR ;
Black, DM ;
Thompson, DE ;
Applegate, WB ;
Barrett-Connor, E ;
Musliner, TA ;
Palermo, L ;
Prineas, R ;
Rubin, SM ;
Scott, JC ;
Vogt, T ;
Wallace, R ;
Yates, AJ ;
LaCroix, AZ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 280 (24) :2077-2082
[4]  
*EUR COMM, 1998, REP OST EUR COMM
[5]   Standardization of BMD measurements [J].
Formica, CA .
OSTEOPOROSIS INTERNATIONAL, 1998, 8 (01) :1-3
[6]   PREDICTING FRACTURES IN WOMEN BY USING FOREARM BONE DENSITOMETRY [J].
GARDSELL, P ;
JOHNELL, O ;
NILSSON, BE .
CALCIFIED TISSUE INTERNATIONAL, 1989, 44 (04) :235-242
[7]  
Garnero P, 1996, J BONE MINER RES, V11, P1531
[8]   ROLE OF PEAK BONE MASS AND BONE LOSS IN POSTMENOPAUSAL OSTEOPOROSIS - 12 YEAR STUDY [J].
HANSEN, MA ;
OVERGAARD, K ;
RIIS, BJ ;
CHRISTIANSEN, C .
BMJ-BRITISH MEDICAL JOURNAL, 1991, 303 (6808) :961-964
[9]   AGE AND BONE MASS AS PREDICTORS OF FRACTURE IN A PROSPECTIVE-STUDY [J].
HUI, SL ;
SLEMENDA, CW ;
JOHNSTON, CC .
JOURNAL OF CLINICAL INVESTIGATION, 1988, 81 (06) :1804-1809
[10]  
Johnell O, 2002, OSTEOPOROSIS INT, V13, pS69