Thalidomide for the treatment of acquired immunodeficiency syndrome-associated refractory oral ulcers

被引：5

作者：

Dios, PD

Sopeña, B

Cameselle, J

Butrón, M

Crespo, M

Ocampo, A

机构：

[1] Univ Santiago de Compostela, Special Needs Unit, Sch Med & Dent, Santiago De Compostela, Spain

[2] Xeral Cies Hosp, Infect Dis Sect, Dept Internal Med, Vigo, Spain

[3] Xeral Cies Hosp, Dept Pathol, Vigo, Spain

来源：

ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY | 2000年 / 126卷 / 01期

关键词：

D O I：

10.1001/archotol.126.1.89

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 [耳鼻咽喉科学];

摘要：

A case of severe, oral, not otherwise specified ulcers in a human immunodeficiency virus-infected patient is described. The lesions did not respond to acyclovir, prednisone, pentoxifylline, or foscarnet sodium therapy. Dramatic clinical improvement and progressive ulcer healing were observed after starting oral thalidomide therapy. Clinicians should be aware of the usefulness of thalidomide for the treatment of acquired immunodeficiency syndrome-associated not otherwise specified ulcerations.

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收藏

页码：89 / 92

页数：4

相关论文

共 20 条

[1]

APHTHOUS ULCERATION OF THE GASTROINTESTINAL-TRACT IN PATIENTS WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME (AIDS) [J].

BACH, MC ;

HOWELL, DA ;

VALENTI, AJ ;

SMITH, TJ ;

WINSLOW, DL .

ANNALS OF INTERNAL MEDICINE, 1990, 112 (06) :465-467

[2]

BIRUKRANT D, 1997, NEW ENGL J MED, V337, P1086

[3]

Behcet disease and the emergence of thalidomide [J].

Ehrlich, GE .

ANNALS OF INTERNAL MEDICINE, 1998, 128 (06) :494-495

[4]

THE PREVALENCE OF ORAL LESIONS IN HIV-INFECTED HOMOSEXUAL AND BISEXUAL MEN - 3 SAN-FRANCISCO EPIDEMIOLOGIC COHORTS [J].

FEIGAL, DW ;

KATZ, MH ;

GREENSPAN, D ;

WESTENHOUSE, J ;

WINKELSTEIN, W ;

LANG, W ;

SAMUEL, M ;

BUCHBINDER, SP ;

HESSOL, NA ;

LIFSON, AR ;

RUTHERFORD, GW ;

MOSS, A ;

OSMOND, D ;

SHIBOSKI, S ;

GREENSPAN, JS .

AIDS, 1991, 5 (05) :519-525

[5]

Ficarra G, 1997, Oral Dis, V3 Suppl 1, pS183

[6]

THALIDOMIDE - TREATMENT OF CHOICE FOR APHTHOUS ULCERS IN PATIENTS SEROPOSITIVE FOR HUMAN-IMMUNODEFICIENCY-VIRUS [J].

GHIGLIOTTI, G ;

REPETTO, T ;

FARRIS, A ;

ROY, MT ;

DEMARCHI, R .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1993, 28 (02) :271-272

[7]

HAGLETT P, 1997, CLIN INFECT DIS, V24, P1223

[8]

Thalidomide in the treatment of the mucocutaneous lesions of the Behcet syndrome - A randomized, double-blind, placebo-controlled trial [J].

Hamuryudan, V ;

Mat, C ;

Saip, S ;

Ozyazgan, Y ;

Siva, A ;

Yurdakul, S ;

Zwingenberger, K ;

Yazici, H .

ANNALS OF INTERNAL MEDICINE, 1998, 128 (06) :443-+

[9]

AN EVALUATION OF ORAL ULCERS IN PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX [J].

LIANG, GS ;

DAIKOS, GL ;

SERFLING, U ;

ZHU, WY ;

PECORARO, M ;

LEONARDI, CL ;

FISCHL, MA ;

PENNEYS, NS .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1993, 29 (04) :563-568

[10]

MacPhail L A, 1997, Oral Dis, V3 Suppl 1, pS190