Esophageal atresia in Osaka: A review of 39 years' experience

被引:48
作者
Okada, A
Usui, N
Inoue, M
Kawahara, H
Kubota, A
Imura, K
Kamata, S
机构
[1] OSAKA PREFECTURAL MED & RES INST MOTHER & CHILD H,OSAKA,JAPAN
[2] KINKI UNIV,SCH MED,DEPT SURG 2,OSAKA 589,JAPAN
关键词
esophageal atresia; tracheo-esophageal fistula; neonatal surgery; risk factor; cardiovascular anomaly;
D O I
10.1016/S0022-3468(97)90455-3
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background: One hundred fifty-nine patients who had eso phageal atresia with or with out tracheoesophageal fistula have been treated at Osaka University Medical School and its affiliated hospitals since the initial (Japanese) experience of Dr T. Ueda in 1957. Methods: These cases were divided chronologically into three groups, With earlier recognition of surgical neonates and the development of perinatal care, the long-term survival of these patients has steadily improved over 39 years from 28% in the first period (1957 to 1967) to 80% in the third period (1980 to 1995). Of 141 patients treated in the second and third periods (1968 to 1995), 92 (65.2%) had associated anomalies. Cardiovascular and gastrointestinal malformations were the most frequently seen major anomalies. VATER or VACTER association was seen in 12.8% (18 of 141) of these patients. Survival of these cases according to Waterston risk factors was 100% for group A, 100% for group B, and 50% for group C, whereas the new classification proposed by Spitz showed survival of 92% for group 1, 50% for group 2, and 0% for group 3, showing better differentiation among the three groups. Results: There was a long gap between the proximal and distal esophageal ends in seven patients (type A), in all of whom primary anastomosis was possible after 28 to 128 days of elongation by bouginage. Although the survival of esophageal atresia patients dramatically improved in recent years, there is still a high incidence of early and long-term postoperative complications, ie, anastomotic leakage (26.5%), recurrent fistula (7.2%), anastomotic struture (49.1%), postoperative pneumonia or atelectasis (57.0%), tracheomalacia (25.8%), and gastroesophageal reflux (52.0%). Conclusions: Recently, there have been changing patterns in the occurrence of complications, which are mainly attributed to technical improvement, better perinatal care and early recognition of pathophysiologic conditions such as tracheomalacia and gastroesophageal reflux. Copyright (C) 1997 by W.B. Saunders Company.
引用
收藏
页码:1570 / 1574
页数:5
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