A meta-analysis of prior corticosteroid use and fracture risk

被引:539
作者
Kanis, JA
Johansson, H
Oden, A
Johnell, O
de Laet, C
Melton, LJ
Tenenhouse, A
Reeve, J
Silman, AJ
Pols, HAP
Eisman, JA
McCloskey, EV
Mellstrom, D
机构
[1] Univ Sheffield, Sch Med, Ctr Metab Bone Dis, WHO Collaborating Ctr, Sheffield S10 2RX, S Yorkshire, England
[2] Malmo Gen Hosp, Dept Orthopaed, S-21401 Malmo, Sweden
[3] Erasmus Univ, Med Ctr, Inst Publ Hlth, Rotterdam, Netherlands
[4] Mayo Clin, Div Epidemiol, Rochester, MN USA
[5] Montreal Gen Hosp, Div Bone Metab, Montreal, PQ H3G 1A4, Canada
[6] Worts Causeway, Strangeways Res Lab, Cambridge, England
[7] Univ Manchester, ARC Epidemiol Unit, Manchester, Lancs, England
[8] Erasmus Univ, Dept Internal Med, Rotterdam, Netherlands
[9] Garvan Inst Med Res, Bone & Minral Res Program, Sydney, NSW, Australia
[10] Univ Gothenburg, Dept Geriatr Med, Gothenburg, Sweden
关键词
corticosteroids; fracture risk; meta-analysis; fracture threshold;
D O I
10.1359/JBMR.040134
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The relationship between use of corticosteroids and fracture risk was estimated in a meta-analysis of data from seven cohort studies of similar to42,000 men and women. Current and past use of corticosteroids was an important predictor of fracture risk that was independent of prior fracture and BMD.
引用
收藏
页码:893 / 899
页数:7
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