Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

被引：232

作者：

Carson, Louise ^{[1
]}

Chau, Peter K. W. ^{[1
]}

Earle, Martyn J. ^{[2
]}

Gilea, Manuela A. ^{[2
]}

Gilmore, Brendan F. ^{[1
]}

Gorman, Sean P. ^{[1
]}

McCann, Maureen T. ^{[1
]}

Seddon, Kenneth R. ^{[2
]}

机构：

[1] Queens Univ Belfast, Sch Pharm, Ctr Med Biol, Belfast BT9 7BL, Antrim, North Ireland

[2] Queens Univ Belfast, QUILL Res Ctr, Sch Chem, Belfast BT9 5AG, Antrim, North Ireland

来源：

GREEN CHEMISTRY | 2009年 / 11卷 / 04期

基金：

英国工程与自然科学研究理事会;

关键词：

CALGARY BIOFILM DEVICE; ANTIMICROBIAL ACTIVITIES; BACTERIAL BIOFILMS; IMIDAZOLIUM; RESISTANCE; TOXICITY; SOLVENTS; SUSCEPTIBILITY; TECHNOLOGY; MECHANISMS;

D O I：

10.1039/b821842k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Microbial biofilms are ubiquitous in nature and represent the predominant mode of growth of microorganisms. A general characteristic of biofilm communities is that they tend to exhibit significant tolerance to antimicrobial challenge compared with planktonic bacteria of the same species The antibiofilm activity of a series of 1-alkyl-3-methylimidazolium chloride ionic liquids has been evaluated against a panel of clinically significant microbial pathogens, including MRSA. A comparison of antimicrobial activity against planktonic bacteria and established biofilms is presented. In general, these ionic liquids possess potent, broad spectrum antibiofilm activity.

引用

页码：492 / 497

页数：6

共 53 条

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