Poststroke depression in patients with small subcortical infarcts

被引：11

作者：

Chen, Yangkun ^{[1
,2
]}

Chen, Xiangyan ^{[2
]}

Mok, Vincent C. T. ^{[2
]}

Lam, Wynnie W. M. ^{[3
]}

Wong, Ka Sing ^{[2
]}

Tang, Wai Kwong ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, Dept Med & Therapeut, Hong Kong, Hong Kong, Peoples R China

[3] Chinese Univ Hong Kong, Dept Diagnost Radiol & Organ Imaging, Hong Kong, Hong Kong, Peoples R China

来源：

CLINICAL NEUROLOGY AND NEUROSURGERY | 2009年 / 111卷 / 03期

关键词：

Small vessel disease; Intracranial large artery disease; Carotid artery stenosis; Depression; Stroke; MRI; CEREBRAL-ARTERY STENOSIS; WEIGHTED MRI; STROKE; DISEASE; MECHANISMS; TERRITORY; SCALE;

D O I：

10.1016/j.clineuro.2008.10.008

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

Objectives: Small subcortical infarcts (SSIs) can result from small vessel disease (SVD) and intracranial and extracranial large artery disease (LAD). No study has explored poststroke depression (PSD) in different etiological types of SSIs. Methods: Patients with SSIs resulting from LAD and SVD were included in the study. Poststroke depression was evaluated with the 15-item version of the geriatric depression scale (GDS) 3 months after stroke. Results: Of the 127 patients with SSIs, 44 had LAD and 83 had SVD. The LAD group had a significantly higher mean GDS score and higher frequency of PSD (p < 0.05). The etiological type LAD was a significant independent risk factor for PSD. Conclusion: PSD is more common in patients with SSIs resulting from LAD. This suggests that cerebral blood perfusion may play an important role in the development of PSD. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：256 / 260

页数：5

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