Social Regulation of Human Gene Expression

被引:119
作者
Cole, Steve W. [1 ,2 ,3 ]
机构
[1] Univ Calif Los Angeles, Dept Med, Sch Med, Div Hematol Oncol, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, AIDS Inst, Cousins Ctr PNI, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Inst Mol Biol, Los Angeles, CA 90095 USA
关键词
genetics; genomics; social factors; gene-environment interactions; STRESS; MECHANISMS; POLYMORPHISM; INTEGRATION; DEPRESSION; RESPONSES; DISEASE; HEALTH; TIES;
D O I
10.1111/j.1467-8721.2009.01623.x
中图分类号
B84 [心理学];
学科分类号
010107 [宗教学];
摘要
The relationship between genes and social behavior has historically been construed as a one-way street, with genes in control. Recent analyses have challenged this view, by discovering broad alterations in the expression of human genes as a function of differing socio-environmental conditions. The emerging field of social genomics has begun to identity the types of genes subject to social regulation, the biological signaling pathways mediating those effects, and the genetic polymorphisms that moderate socioenvironmental influences on human gene expression.
引用
收藏
页码:132 / 137
页数:6
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