Ghrelin: update on a novel hormonal system

被引：59

作者：

Korbonits, M ^{[1
]}

Grossman, AB ^{[1
]}

机构：

[1] Univ London St Bartholomews Hosp Med Coll, Dept Endocrinol, London EC1A 7BE, England

来源：

EUROPEAN JOURNAL OF ENDOCRINOLOGY | 2004年 / 151卷

关键词：

D O I：

10.1530/eje.0.151S067

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Ghrelin is a peptide hormone secreted into the circulation from the stomach but also synthesised in a number of tissues, suggesting both endocrine and paracrine effects. These include: stimulation of GH, prolactin and ACTH secretion: an increase in appetite; a diabetogenic effect on carbohydrate metabolism; positive inotropic effects on heart; vasodilatation; and effects on cell proliferation. The possibility of chronic manipulation of the ghrelin system on body weight, growth and appetite remains an exciting new field of exploration.

引用

页码：S67 / S70

页数：4

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