Periodic adhesive fingers between contacting cells -: art. no. 108102

被引：22

作者：

Delanoë-Ayari, H

Lenz, P

Brevier, J

Weidenhaupt, M

Vallade, M

Gulino, D

Joanny, JF

Riveline, D ^{[1
]}

机构：

[1] Univ Grenoble 1, Spectrometrie Phys Lab, CNRS, UMR 5588, F-38402 St Martin Dheres, France

[2] Inst Curie, UMR 168, Paris, France

[3] Univ Marburg, Fachbereich Phys, D-35032 Marburg, Germany

[4] Inst Biol Struct, LIM, Grenoble, France

来源：

PHYSICAL REVIEW LETTERS | 2004年 / 93卷 / 10期

关键词：

D O I：

10.1103/PhysRevLett.93.108102

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We study in detail the properties of fingers, a particular type of cell-cell adhesive structures appearing in adherens junctions. These periodic patterns break the symmetry of cell-cell contacts. We show that finger formation is driven by cadherin interactions and actin growth. A theoretical model is introduced in which the growth of fingers is limited by membrane tension. The steady shape and formation kinetics of fingers are experimentally measured and compared with the theoretical predictions.

引用

页码：108102 / 1

页数：4

共 31 条

[1] Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein [J].