Deaths from pertussis are underestimated in England

被引:93
作者
Crowcroft, NS
Andrews, N
Rooney, C
Brisson, M
Miller, E
机构
[1] Publ Hlth Lab Serv, Ctr Communicable Dis Surveillance, Immunisat Div, London NW9 5EQ, England
[2] Off Natl Stat, London SW1V 2QQ, England
关键词
D O I
10.1136/adc.86.5.336
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Aims: To improve estimates of deaths from pertussis in England and to identify reasons for under ascertainment. Methods: Comparison of deaths identified from enhanced laboratory pertussis surveillance, hospital episode statistics (HES), and Office for National Statistics (ONS) death registrations in England, 1994 to 1999. Results: A total of 33 deaths were identified, 88% of infants less than 4 months old. There was overlap between all sources; 22 deaths were identified in the enhanced pertussis surveillance system, 18 in ONS mortality data, and nine in HES. Children who had died from pertussis without mention of pertussis on the death certificate were more likely to have been certified by coroners than those with mention of pertussis (p = 0.0005). Using capture-recapture analysis, the total number of deaths from pertussis in the five and a half year period is estimated to be 46 (95% CI 37 to 71), or around nine deaths per year. Conclusions: National mortality statistics significantly under estimate deaths from pertussis in England and are inadequate for monitoring the national immunisation programme. The largest number of deaths is identified through enhanced laboratory surveillance. Death registration systems should take into account available microbiological information to ensure that cause of death is accurately assigned.
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页码:336 / 338
页数:3
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