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Amperometric biosensors based on NAD(P)-dependent dehydrogenase enzymes

被引：212
作者：
Lobo, MJ
Miranda, AJ
Tunon, P
机构：
[1] Depto. de Quim.-Fis. y Analitica, Universidad de Oviedo, E-33006 Oviedo, Asturias
来源：
ELECTROANALYSIS | 1997年 / 9卷 / 03期
关键词：
amperometric biosensors; dehydrogenases; NAD(P)H;
D O I：
10.1002/elan.1140090302
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
This review deals with the use of pyridine-nucleotide dependent dehydrogenase enzymes in amperometric biosensor design. The electrochemistry of the nicotinamide coenzymes, their mechanism and the challenges associated with their direct oxidation on solid electrodes are discussed. In addition, a survey of the different solutions proposed in the literature for addressing these problems and some of their applications are presented.
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页码：191 / 202
页数：12
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