Heck reactions of quinoline-derived nonaflates

被引：11

作者：

Aulenta, Francesca ^{[1
]}

Reissig, Hans-Ulrich ^{[1
]}

机构：

[1] Free Univ Berlin, Inst Chem & Biochem, D-14195 Berlin, Germany

来源：

SYNLETT | 2006年 / 18期

关键词：

Heck coupling; Pd catalysis; nonaflate; samarium(II) iodide; quinoline;

D O I：

10.1055/s-2006-948197

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of a series of quinolyl-substituted ketones or ketone precursors via the Heck reaction of 6- or 8-quinolyl nonaflates with an appropriate selection of olefins is presented. These ketones are useful building blocks for the diastereoselective construction of azapolycycles via SmI2-induced intramolecular cyclization of (het)aryl-substituted ketones.

引用

页码：2993 / 2996

页数：4

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