A novel, multiple drug-resistant, serotype 24F strain of Streptococcus pneumoniae that caused meningitis in patients in Naples, Italy

被引：30

作者：

Pantosti, A

Gherardi, G

Conte, M

Faella, F

Dicuonzo, G

Beall, B

机构：

[1] Ist Super Sanita, Batteriol & Micol Med Lab, I-00161 Rome, Italy

[2] Dipartimento Med Lab & Microbiol, Rome, Italy

[3] Azienda Ospedaliera D Cotugno, Ctr Neuropatie Infett, Naples, Italy

[4] Azienda Ospedaliera D Cotugno, Lab Anal Chim Clin & Microbiol, Naples, Italy

[5] Ctr Dis Control & Prevent, Natl Ctr Infect Dis, Atlanta, GA USA

来源：

CLINICAL INFECTIOUS DISEASES | 2002年 / 35卷 / 02期

关键词：

D O I：

10.1086/341250

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Three adult patients in Naples, Italy, had meningitis due to multiple drug-resistant serotype 24F Streptococcus pneumoniae isolates. The 3 isolates were genetically indistinguishable and shared pbp2b and pspA sequence types with previously characterized penicillin-resistant clones. This serotype 24F strain was found to be the same clonal type as a previously characterized, penicillin-resistant serotype 14 strain. The novel strain has probably arisen through transformation of a serotype 14 strain with type 24F capsular biosynthetic operon sequences.

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页码：205 / 208

页数：4

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