Pre-metrological (pre-analytical) variation of some biochemical quantities

被引：17

作者：

Fuentes-Arderiu, X ^{[1
]}

Acebes-Frieyro, G ^{[1
]}

Gavaso-Navarro, L ^{[1
]}

Castiñeiras-Lacambra, MJ ^{[1
]}

机构：

[1] Ciutat Sanitaria & Univ Bellvitge, Serv Bioquim Clin, Lhospitalet De Llobregat 08907, Catalonia, Spain

来源：

CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 1999年 / 37卷 / 10期

关键词：

pre-metrological variation; pre-analytical variation; uncertainty of measurement;

D O I：

10.1515/CCLM.1999.146

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

It is customary to assume that pre-metrological variation is negligible if all pre-metrological sources of variation have been standardised. The aim of this study was to quantify the pre-metrological variation of some biochemical quantities frequently measured in clinical laboratories. The experimental design considers the different sources of pre-metrological variation that usually act day-to-day on samples from patients. The results demonstrate that, for many quantities, the pre-metrological variance is not negligible; consequently, it is suggested that these variances should be taken into account when estimating the uncertainty of measurement of patients' results.

引用

页码：987 / 989

页数：3