Localization of the human phosphotyrosine phosphatase-related genes (h-PRL-1) to chromosome bands 1p35-p34, 17q12-q21, 11q24-q25 and 12q24

被引：6

作者：

Montagna, M

Serova, O

Sylla, BS

Mattei, MG

Lenoir, GM

机构：

[1] INT AGCY RES CANC, F-69372 LYON 08, FRANCE

[2] FAC MED MARSEILLE, INSERM U406, UNITE GENET & DEV, F-13385 MARSEILLE, FRANCE

[3] UNIV PADUA, INST ONCOL, I-35128 PADUA, ITALY

来源：

HUMAN GENETICS | 1996年 / 98卷 / 06期

关键词：

D O I：

10.1007/s004390050295

中图分类号：

Q3 [遗传学];

学科分类号：

071007 [遗传学]; 090102 [作物遗传育种];

摘要：

The h-PRt-1 gene codes for a new phosphotyrosine phosphatase that may play an important role in the control of basic cellular processes such as: cell growth and proliferation, Using the cDNA of the h-PRL-1 gene as a probe, we examined a somatic mouse and hamster x human hybrid panel and found that chromosomes 1, 17 and Il harbor sequences homologous to h-PRL-1, By in situ hybridization of metaphase spreads, subchromosomal localizations were determined al bands 1p35-p34, 17q12-q21 and 11q24-q25: in addition, a faint signal was detected at 12q24, The chromosomal assignment of the genes homologous to h-PRL-1 will help the investigation of its possible involvement in human diseases involving genetic alteration at these chromosomal regions.

引用

页码：738 / 740

页数：3

共 7 条

[1]

PRL-1, A UNIQUE NUCLEAR-PROTEIN TYROSINE PHOSPHATASE, AFFECTS CELL-GROWTH [J].

DIAMOND, RH ;

CRESSMAN, DE ;

LAZ, TM ;

ABRAMS, CS ;

TAUB, R .

MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (06) :3752-3762

[2]

LOSS OF HETEROZYGOSITY FOR THE SHORT ARM OF CHROMOSOME-1 IN HUMAN NEUROBLASTOMAS - CORRELATION WITH N-MYC AMPLIFICATION [J].

FONG, CT ;

DRACOPOLI, NC ;

WHITE, PS ;

MERRILL, PT ;

GRIFFITH, RC ;

HOUSMAN, DE ;

BRODEUR, GM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (10) :3753-3757

[3]

RECEPTOR PROTEIN-TYROSINE PHOSPHATASE-GAMMA IS A CANDIDATE TUMOR SUPPRESSOR GENE AT HUMAN-CHROMOSOME REGION 3P21 [J].

LAFORGIA, S ;

MORSE, B ;

LEVY, J ;

BARNEA, G ;

CANNIZZARO, LA ;

LI, F ;

NOWELL, PC ;

BOGHOSIANSELL, L ;

GLICK, J ;

WESTON, A ;

HARRIS, CC ;

DRABKIN, H ;

PATTERSON, D ;

CROCE, CM ;

SCHLESSINGER, J ;

HUEBNER, K .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (11) :5036-5040

[4]

Mitelman F, 1993, HUMAN GENE MAPPING, P773

[5]

MONTAGNA M, 1995, HUM GENET, V96, P532

[6]

STRUCTURE, MAPPING, AND EXPRESSION OF ERP, A GROWTH FACTOR-INDUCIBLE GENE ENCODING A NONTRANSMEMBRANE PROTEIN-TYROSINE-PHOSPHATASE, AND EFFECT OF ERP ON CELL-GROWTH [J].

NOGUCHI, T ;

METZ, R ;

CHEN, LH ;

MATTEI, MG ;

CARRASCO, D ;

BRAVO, R .

MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (09) :5195-5205

[7]

STONE RL, 1994, J BIOL CHEM, V269, P31323

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