Thermolysis of N,N"-1,ω-alkanediyl-bis[N′-organylthiourea] derivatives

被引：12

作者：

Hassan, Alaa A. ^{[1
]}

Doepp, Dietrich

机构：

[1] Menia Univ, Fac Sci, Dept Chem, El Minia, Egypt

[2] Univ Duisburg Essen, D-47048 Duisburg, Germany

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2006年 / 43卷 / 03期

关键词：

D O I：

10.1002/jhet.5570430311

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The course of microwave assisted or conventional thermal intramolecular heterocyclization of the title compounds has been found to be dependent on the length of the alkanediyl chain. While 1,3-propanediyl-bisthioureas 5a-c gave both 2-thioxoperhydropyrimidine-1-carbothioamides 8a-c and 8-amino-3,4,5,6-tetrahydro-1,3,7-thiadiazocine-2-thiones 10a-c, thermolysis of 1,4-butanediyl-bisthioureas 6a-c and 1,6-hexanediyl-bisthioureas 7a-c under the same conditions gave solely 9-amino-4,5,6,7-tetrahydro-1,3,8-thiadiazonine-2-thiones 11a-c and 11-amino-1-thia-3,10-diazacycloundec-10-ene-2-thiones 12a-c, respectively. Symmetric N,N'-diorganylthioureas 4a-c were formed in all cases as minor byproducts.

引用

页码：593 / 598

页数：6

共 25 条

[1]

Synthesis of symmetrical N,N′-disubstituted thioureas and heterocyclic thiones from amines and CS2 over a ZnO/Al2O3 composite as heterogeneous and reusable catalyst [J].