Solitary fibrous tumor involving the renal capsule

被引:105
作者
Gelb, AB
Simmons, ML
Weidner, N
机构
[1] Department of Pathology, University of California, San Francisco, CA
[2] Department of Pathology, M590, University of California, San Francisco, CA 94143-0102
关键词
solitary fibrous tumor; immunohistochemistry; CD34; desmin; keratin; S100; protein; electron microscopy; kidney;
D O I
10.1097/00000478-199610000-00016
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Solitary fibrous tumors are spindle-cell neoplasms that originally were described in the pleura but that can occur in a large variety of sites, We report a well-circumscribed tumor, apparently involving the renal capsule, clinically thought to be a renal-cell carcinoma or oncocytoma. it was composed of bland spindle-shaped cells with a patchy lymphoplasmacytic infiltrate, suggesting sarcomatoid renal-cell carcinoma, inflammatory myofibroblastic tumor, or solitary fibrous tumor; however, immunohistochemical stains were negative for keratin, alpha-smooth-muscle actin, and desmin but strongly positive for CD34. Ultrastructural examination revealed fibroblast-like cells without myofibroblastic or epithelial differentiation. The combined findings favor a diagnosis of a solitary fibrous tumor involving the renal capsule. To our knowledge, this lesion has not been reported in this location.
引用
收藏
页码:1288 / 1295
页数:8
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