A novel synthesis of disubstituted ureas using titanium(IV) isopropoxide and sodium borohydride

被引：36

作者：

Armstrong, JD ^{[1
]}

Wolfe, CN ^{[1
]}

Keller, JL ^{[1
]}

Lynch, J ^{[1
]}

Bhupathy, M ^{[1
]}

Volante, RP ^{[1
]}

DeVita, RJ ^{[1
]}

机构：

[1] MERCK & CO INC,MERCK SHARP & DOHME RES LABS,DEPT MED CHEM,RAHWAY,NJ 07065

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 09期

关键词：

D O I：

10.1016/S0040-4039(97)00149-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This paper describes a high yield preparation of unsymmetrically disubstituted ureas by a titanium(IV) isopropoxide/sodium borohydride mediated reductive amidation of aromatic aldehydes with monosubstituted ureas. (C) 1997 Elsevier Science Ltd.

引用

页码：1531 / 1532

页数：2

共 10 条

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