Carrageenans from chilean samples of Stenogramme interrupta (Phyllophoraceae):: structural analysis and biological activity

被引：110

作者：

Cáceres, PJ

Carlucci, MJ

Damonte, EB

Matsuhiro, B

Zúñiga, EA

机构：

[1] Univ Santiago Chile, Dept Ciencias Quim, Santiago 33, Chile

[2] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Quim Biol, Virol Lab, RA-1428 Buenos Aires, DF, Argentina

来源：

PHYTOCHEMISTRY | 2000年 / 53卷 / 01期

关键词：

Stenogramme interrupta; carrageenans; nuclear phases; natural antiviral; anticoagulant activity;

D O I：

10.1016/S0031-9422(99)00461-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Carrageenans extracted from cystocarpic and tetrasporic Stenogramme interrupta were analysed by chemical and spectroscopic methods. The carrageenan from cystocarpic plants is composed predominantly of 0.5 M KCl-insoluble and 1 M KCl-soluble fractions. The insoluble fraction contained iota-carrageenan as the major component with alpha-carrageenan and pyruvated carrageenan as minor components. The soluble fraction is highly heterogeneous and did not contain the precursors mu- and nu-carrageenans. The polysaccharide from tetrasporic plants is composed of xi- and lambda-carrageenans, and low sulfated galactans. It is soluble in KCl and partly cyclized by alkaline treatment. The antiviral and anticoagulant properties of the insoluble polysaccharide fraction from cystocarpic S. interrupta and the polysaccharide from tetrasporic S. interrupta are reported the results of which suggest promising antiherpetic activity. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：81 / 86

页数：6

共 45 条

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