Grade of adiposity affects the impact of fat mass on resting energy expenditure in women

被引:39
作者
Bosy-Westphal, Anja [1 ]
Mueller, Manfred J. [1 ]
Boschmann, Michael [2 ]
Klaus, Susanne [3 ]
Kreymann, Georg [4 ]
Luehrmann, Petra M. [5 ]
Neuhaeuser-Berthold, Monika [5 ]
Noack, Rudolf [3 ]
Pirke, Karl M. [6 ]
Platte, Petra [7 ]
Selberg, Oliver [8 ]
Steiniger, Jochen [9 ]
机构
[1] Univ Kiel, Inst Humanernahrung & Lebensmittelkunde, Agrar & Ernahrungswissensch Fak, D-24105 Kiel, Germany
[2] Franz Volhard Centrum Klin Forsch, D-13122 Berlin, Germany
[3] Abteilung Biochem & Physiol Ernahrung, Deutsch Inst Ernahrungsforsch, D-14558 Potsdam, Germany
[4] Univ Krankenhaus Eppendorf, Med Klin, D-20251 Hamburg, Germany
[5] Univ Giessen, Inst Ernahrungswissensch, D-35390 Giessen, Germany
[6] Univ Trier, Forschungszentrum Psychobiol & Psychosomat, D-54286 Trier, Germany
[7] Univ Wurzburg, Biol & Klin Psychol, D-97070 Wurzburg, Germany
[8] Klinikum Stadt Ludwigshafen, Inst Mikrobiol Immunol & Krankenhaushyg, D-38114 Braunschweig, Germany
[9] Herbert Krauss Klin, Klinikum Berlin Buch, D-13122 Berlin, Germany
关键词
Resting energy expenditure; Fat mass; Fat-free mass; Women; BODY-WEIGHT REGULATION; BASAL METABOLIC-RATE; OBESE; PREDICTION; AGE; MITOCHONDRIA; DYSFUNCTION; EQUATIONS; TISSUE; LEPTIN;
D O I
10.1017/S0007114508020357
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Body fat mass (FM) adds to the variance in resting energy expenditure (REE). However, the nature and extent of this relationship remains unclear. Using a database of 1306 women and a linear regression model, we systematically analysed the contribution of FM to the total variance in REE at different grades of adiposity (ranges of body %FM). After adjusting for age, the relative contribution of FM on REE variance increased from low (<= 10%FM) to normal (> 10- <= 30 %FM) and moderately elevated (>30- <= 40%FM) grades of adiposity but decreased sharply at high (>40- <= 50 %FM) and very high (> 50 %FM) grades of adiposity according to the ratio between regression coefficients. These data suggest that the specific metabolic rate of fat tissue is reduced at high adiposity. This should be considered when REE is normalized for FM in obesity.
引用
收藏
页码:474 / 477
页数:4
相关论文
共 23 条
[1]   PREDICTION OF THE RESTING METABOLIC-RATE IN OBESE PATIENTS [J].
BERNSTEIN, RS ;
THORNTON, JC ;
YANG, MU ;
WANG, J ;
REDMOND, AM ;
PIERSON, RN ;
PISUNYER, FX ;
VANITALLIE, TB .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1983, 37 (04) :595-602
[2]   The age-related decline in resting energy expenditure in humans is due to the loss of fat-free mass and to alterations in its metabolically active components [J].
Bosy-Westphal, A ;
Eichhorn, C ;
Kutzner, D ;
Illner, K ;
Heller, M ;
Müller, MJ .
JOURNAL OF NUTRITION, 2003, 133 (07) :2356-2362
[3]   Mitochondria are impaired in the adipocytes of type 2 diabetic mice [J].
Choo, HJ ;
Kim, JH ;
Kwon, OB ;
Lee, CS ;
Mun, JY ;
Han, SS ;
Yoon, YS ;
Yoon, G ;
Choi, KM ;
Ko, YG .
DIABETOLOGIA, 2006, 49 (04) :784-791
[4]   BODY-COMPOSITION AS A DETERMINANT OF ENERGY-EXPENDITURE - A SYNTHETIC REVIEW AND A PROPOSED GENERAL PREDICTION EQUATION [J].
CUNNINGHAM, JJ .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1991, 54 (06) :963-969
[5]  
ELIA M, 1992, ENERGY METABOLISM, P61
[6]  
FERRARO R, 1992, AM J CLIN NUTR, V56, P460
[7]   The Harris-Benedict studies of human basal metabolism: History and limitations [J].
Frankenfield, DC ;
Muth, ER ;
Rowe, WA .
JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION, 1998, 98 (04) :439-445
[8]  
GARBY L, 1988, EUR J CLIN NUTR, V42, P301
[9]   Leptin and body weight regulation in patients with anorexia nervosa before and during weight recovery [J].
Haas, V ;
Onur, S ;
Paul, T ;
Nutzinger, DO ;
Bosy-Westphal, A ;
Hauer, M ;
Brabant, G ;
Klein, H ;
Müller, MJ .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2005, 81 (04) :889-896
[10]   INFLUENCE OF AGE, FAT-CELL WEIGHT, AND OBESITY ON O-2 CONSUMPTION OF HUMAN ADIPOSE-TISSUE [J].
HALLGREN, P ;
SJOSTROM, L ;
HEDLUND, H ;
LUNDELL, L ;
OLBE, L .
AMERICAN JOURNAL OF PHYSIOLOGY, 1989, 256 (04) :E467-E474