A one-pot procedure for the synthesis of alkynes and bromoalkynes from aldehydes

被引：82

作者：

Michel, P

Gennet, D

Rassat, A

机构：

[1] Ecole Normale Super, F-75231 Paris 05, France

[2] CNRS, F-75231 Paris, France

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 49期

关键词：

alkynes; bromoalkynes; dibromomethyltriphenylphosphonium bromide; ylids;

D O I：

10.1016/S0040-4039(99)01830-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alkynes R-C=CH were obtained in good yield through a one-pot procedure by a sequence of reactions starting from a Wittig-type condensation of the aldehydes RCHO with the ylide derived from dibromomethyltriphenylphosphonium bromide 5. The same reactions could also be used to prepare the intermediate dibromoalkenes RCH=CBr2, and in certain cases, the bromoalkynes R-C=CBr. (C) 1999 Elsevier Science Ltd. All rights reserved.

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收藏

页码：8575 / 8578

页数：4

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